Double-PFG Diffusion-Diffraction in Ellipsoidal Pores

Repeated application of diffusion gradient pulse pairs [1] in a pulsed field gradient (PFG) experiment provides important insights into pore microstructure. For example, the dimensions and eccentricity of yeast cells were measured from the fourth order term of the double-PFG signal attenuation when the mixing time between the two encoding blocks is long [2]. In this abstract, we propose an alternative double-PFG technique to address the same problem, which exploits the diffusion-diffraction phenomenon [3] in double-PFG experiments [4]. In our approach, all diffusion gradients in a single acquisition are applied along the same direction with a mixing time of 0. The experiment is subsequently repeated with diffusion gradients applied along different directions.